Description

tert-Butyl 4-(4-Ethyl-3-Iodophenyl)-4-Methyl-3-Oxopentanoate is a high-purity, advanced pharmaceutical intermediate characterized by its complex molecular structure featuring a tert-butyl ester and an iodophenyl moiety. This compound is critical for enabling precise chemical transformations in the synthesis of novel active pharmaceutical ingredients (APIs), offering researchers a reliable building block with consistent reactivity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) due to the presence of the iodine atom.
• Agrochemical Research: Used in the development and synthesis of new active ingredients for crop protection products.
• Material Science Precursor: Can be employed in the research of organic electronic materials and liquid crystals.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for methodological studies and novel synthetic route exploration.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.

Basic Information

Product Name	tert-Butyl 4-(4-Ethyl-3-Iodophenyl)-4-Methyl-3-Oxopentanoate
CAS No.	1256584-74-3
Molecular Formula	C18H25IO3
Molecular Weight	416.30 g/mol
Synonyms	4-(4-Ethyl-3-iodophenyl)-4-methyl-3-oxopentanoic acid tert-butyl ester; 3-Oxopentanoic acid, 4-(4-ethyl-3-iodophenyl)-4-methyl-, 1,1-dimethylethyl ester; tert-Butyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate; 1,1-Dimethylethyl 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxopentanoate; Pentanoic acid, 4-(4-ethyl-3-iodophenyl)-4-methyl-3-oxo-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Ethyl-3-Iodophenyl)-4-Methyl-3-Oxopentanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.