Description

9-Bromo-8-Hydroxy-6,6-Dimethyl-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a complex polycyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex carbazole-based drug candidates targeting various diseases.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study biological pathways and protein interactions.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing complex heterocyclic compounds due to its reactive bromo, hydroxy, and nitrile functional groups.
• Material Science Research: Potential precursor for organic electronic materials given its extended conjugated carbazole core.

Basic Information

Product Name	9-Bromo-8-Hydroxy-6,6-Dimethyl-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile
CAS No.	1256579-06-2
Molecular Formula	C19H13BrN2O2
Molecular Weight	381.23 g/mol
Synonyms	9-Bromo-8-hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; 5H-Benzo[b]carbazole-3-carbonitrile, 9-bromo-6,11-dihydro-8-hydroxy-6,6-dimethyl-11-oxo-; 1256579-06-2; 9-Bromo-8-hydroxy-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; Benzo[b]carbazole derivative CAS 1256579-06-2
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and other critical parameters are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.