Description

5,6,7,8-Tetrahydro-Imidazo[1,2-A]Pyridine-6-Methanol is a high-value heterocyclic building block and chiral intermediate of significant interest in advanced organic synthesis. Its imidazopyridine core fused with a functionalized piperidine ring makes it a versatile scaffold for constructing complex molecular architectures. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a critical precursor for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its complex heterocyclic structure for bioactivity.
• Chemical Synthesis: Serves as a sophisticated precursor in medicinal chemistry for constructing fused bicyclic systems and introducing the methanol functional group for further derivatization.
• Ligand and Catalyst Development: Potential use in creating chiral ligands for asymmetric catalysis due to its defined stereochemistry and nitrogen-containing heterocycles.
• Academic & Institutional R&D: Employed in university and contract research organizations (CROs) for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	5,6,7,8-Tetrahydro-Imidazo[1,2-A]Pyridine-6-Methanol
CAS No.	1256546-79-8
Molecular Formula	C9H14N2O
Molecular Weight	166.22 g/mol
Synonyms	(6S)-5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-6-ylmethanol; 6-(Hydroxymethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine; Tetrahydroimidazopyridine methanol; Imidazo[1,2-a]pyridine-6-methanol, 5,6,7,8-tetrahydro-; CAS 1256546-79-8
EINECS	Contact for details

Quality Control

Every batch of 5,6,7,8-Tetrahydro-Imidazo[1,2-A]Pyridine-6-Methanol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.