Description

2-Oxaspiro[3.5]Nonan-7-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic oxetane-lactone structure. This compound is valued for its role as a critical building block in the synthesis of complex, bioactive molecules, particularly in modern drug discovery programs. It is primarily sought after by research institutions and pharmaceutical companies engaged in developing novel therapeutics, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for targeted therapies.
• Protease Inhibitor Synthesis: Serves as a core structural component in the construction of potent protease inhibitors for antiviral and anticancer applications.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and improve drug-like properties.
• Organic Synthesis Building Block: Employed in complex multi-step organic syntheses to introduce constrained spirocyclic frameworks into target molecules.
• Bioconjugation & Probe Development: Potential utility in creating chemical probes or bioconjugates for biochemical and diagnostic research due to its reactive carbonyl group.

Basic Information

Product Name	2-Oxaspiro[3.5]Nonan-7-One
CAS No.	1256546-74-3
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	7-Oxaspiro[3.5]nonan-2-one; 2-Oxaspiro[3.5]nonan-7-one; Spiro[3.5]nonane-7-one, 2-oxa-; 7-Oxaspiro[3.5]nonan-2-one; Oxaspiro[3.5]nonan-7-one; 1256546-74-3; 2-Oxa-spiro[3.5]nonan-7-one
EINECS	Contact for details

Quality Control

Every batch of 2-Oxaspiro[3.5]Nonan-7-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support cGMP-compliant production for pharmaceutical applications. A detailed Certificate of Analysis (COA) with specifications for purity (typically ≥95% to ≥98% by HPLC), identity confirmation (IR, NMR), and impurity profiling is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Related Substances (HPLC)	Individual impurity ≤2.0%
Total Impurities	≤5.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.