Description

Diethyl 1,4-Dioxaspiro[4.5]Decane-8,8-Dicarboxylate is a high-value spirocyclic diester building block used in advanced organic synthesis. This compound is critical for the development of complex molecular architectures, offering a rigid, functionalized scaffold that is difficult to access through other routes. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of spirocyclic drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Agrochemical Synthesis: Used to build complex, bioactive molecules for the development of new-generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Asymmetric Catalysis Ligand Precursor: The spirocyclic framework can be elaborated into chiral ligands for use in enantioselective catalytic reactions.
• Fragrance and Flavor Chemistry: Potential intermediate for synthesizing complex, musk-like or woody fragrance compounds due to its constrained bicyclic structure.
• Academic and Contract Research: A valuable tool for methodological studies in organic chemistry, particularly in annulation and ring-expansion reactions.

Basic Information

Product Name	Diethyl 1,4-Dioxaspiro[4.5]Decane-8,8-Dicarboxylate
CAS No.	1256546-71-0
Molecular Formula	C15H24O6
Molecular Weight	300.35 g/mol
Synonyms	8,8-Bis(ethoxycarbonyl)-1,4-dioxaspiro[4.5]decane; Diethyl 1,4-Dioxaspiro[4.5]decane-8,8-dicarboxylate; 1,4-Dioxaspiro[4.5]decane-8,8-dicarboxylic Acid Diethyl Ester; Diethyl 8,8-Dicarboxy-1,4-dioxaspiro[4.5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexane]-4',4'-dicarboxylic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl 1,4-Dioxaspiro[4.5]Decane-8,8-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.