Description

(6S)-6-[5-(7-Bromo-9,9-Difluoro-9H-Fluoren-2-Yl)-1H-Imidazol-2-Yl]-5-Azaspiro[2.4]Heptane-5-Carboxylic Acid Phenylmethyl Ester is a sophisticated, high-purity chemical intermediate designed for advanced pharmaceutical research and development. This compound is critical for medicinal chemists seeking to develop novel therapeutic agents, particularly in targeted drug discovery programs. It is primarily utilized by R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery projects.
• Protease Inhibitor Development: Serves as a core scaffold in the design and synthesis of potential protease inhibitors due to its unique spirocyclic and imidazole motifs.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme function and cellular signaling pathways.
• High-Value Fine Chemical Synthesis: Integral in multi-step synthetic routes for producing complex, high-value specialty chemicals.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(6S)-6-[5-(7-Bromo-9,9-Difluoro-9H-Fluoren-2-Yl)-1H-Imidazol-2-Yl]-5-Azaspiro[2.4]Heptane-5-Carboxylic Acid Phenylmethyl Ester
CAS No.	1256388-49-4
Molecular Formula	C33H26BrF2N3O2
Molecular Weight	614.48 g/mol
Synonyms	Benzyl (6S)-6-[5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylate; (6S)-6-[5-(7-Bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro[2.4]heptane-5-carboxylic acid benzyl ester; 5-Azaspiro[2.4]heptane-5-carboxylic acid, 6-[5-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-1H-imidazol-2-yl]-, phenylmethyl ester, (6S)-; UNII-7B2K6I0Q8H; 7B2K6I0Q8H
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems to ensure consistency and reliability for critical research applications. Our quality control protocols include comprehensive analytical characterization using techniques such as HPLC, NMR, and mass spectrometry to verify identity and purity. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.