Description

3-(2-Chloroethoxy)Phenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the chlorinated ethoxy linker provides valuable chemical functionality.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs or conductive films, where the boronic ester group facilitates controlled polymerization.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of chemical probes used in proteomics and diagnostic assay development.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other advanced catalytic processes.

Basic Information

Product Name	3-(2-Chloroethoxy)Phenylboronic Acid, Pinacol Ester
CAS No.	1256359-00-8
Molecular Formula	C14H20BClO3
Molecular Weight	282.57 g/mol
Synonyms	3-(2-Chloroethoxy)benzeneboronic acid pinacol ester; 2-[3-(2-Chloroethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(2-Chloroethoxyphenyl)boronic acid pinacol ester; Pinacol [3-(2-chloroethoxy)phenyl]boronate; 3-(2-Chloroethoxy)phenylboronic acid neopentyl glycol ester (common alternative); B-[3-(2-Chloroethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3-(2-Chloroethoxy)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.