Description

6-Fluoro-1H-Indole-2-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex, fluorinated indole derivatives. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the discovery and production of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to attach complex aryl groups to the indole scaffold.
• Agrochemical Research: Used in the development of new fluorinated pesticides and herbicides with enhanced properties.
• Material Science: Serves as a precursor for creating organic electronic materials and functional polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for biological studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific fluorinated indole architectures.

Basic Information

Product Name	6-Fluoro-1H-Indole-2-Boronic Acid Pinacol Ester
CAS No.	1256358-98-1
Molecular Formula	C₁₄H₁₇BFNO₂
Molecular Weight	261.10 g/mol
Synonyms	6-Fluoro-1H-indol-2-ylboronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-fluoro-1H-indole; 6-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 6-Fluoroindole-2-boronic acid pinacol ester; 6-Fluoro-1H-indole-2-boronic acid, pinacol ester; 6-F-1H-Indole-2-Bpin; B-(6-Fluoro-1H-indol-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1H-Indole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full specification data are provided to guarantee consistent quality and reliable performance in your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.