Description

2-(Piperidin-1-Yl)Pyridin-4-Ylboronic Acid CAS NO 1256358-82-3 is a high-value boronic acid derivative and a crucial organoboron building block for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation, specifically serving as a key intermediate in Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who are developing novel active ingredients, as well as for advanced material scientists working on functional organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, enabling the creation of complex molecular architectures.
• Material Science Research: Serves as a precursor for constructing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as a boronic acid coupling partner to introduce the 2-(piperidin-1-yl)pyridin-4-yl moiety into complex molecules.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysis and organocatalysts.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.

Basic Information

Product Name	2-(Piperidin-1-Yl)Pyridin-4-Ylboronic Acid
CAS No.	1256358-82-3
Molecular Formula	C10H15BN2O2
Molecular Weight	206.06 g/mol
Synonyms	2-(1-Piperidinyl)-4-pyridineboronic Acid; 4-Borono-2-(1-piperidinyl)pyridine; 2-(Piperidin-1-yl)pyridine-4-boronic Acid; 2-Piperidin-1-ylpyridine-4-boronic Acid; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(piperidin-1-yl)pyridine (Pinacol Ester Precursor); 2-(1-Piperidyl)pyridin-4-ylboronic Acid
EINECS	Contact for details

Quality Control

Our 2-(Piperidin-1-Yl)Pyridin-4-Ylboronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.