Description

Pyridine-4-Boronic Acid Hydrate is a versatile and high-value boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in its crucial role as a coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop active pharmaceutical ingredients (APIs), advanced crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those containing pyridine and biphenyl motifs for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or building block for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new C-C bond formation methodologies and creating compound libraries.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Diagnostic Reagents: Can be incorporated into probes and sensors for biochemical detection and analysis.

Basic Information

Product Name	Pyridine-4-Boronic Acid Hydrate
CAS No.	1256355-27-7
Molecular Formula	C5H8BNO3 (anhydrous basis)
Molecular Weight	140.94 g/mol (anhydrous basis)
Synonyms	4-Pyridineboronic Acid Hydrate; 4-Pyridinylboronic Acid Hydrate; (4-Pyridyl)boronic Acid Hydrate; 4-Boronopyridine Hydrate; Pyridin-4-ylboronic Acid Hydrate; PBA Hydrate; 4-PyBA Hydrate; 4-Pyridyl-B(OH)2 Hydrate
EINECS	Contact for details

Quality Control

Our Pyridine-4-Boronic Acid Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.