Description

2-Aza-Spiro[3.3]Heptan-6-Ol CAS NO 1256352-97-2 is a high-value, nitrogen-containing spirocyclic building block of significant interest in modern synthetic chemistry. Its unique rigid, three-dimensional structure makes it a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily sought after by medicinal chemists and process development scientists in the life sciences industry for the discovery and synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold and constrained amine moiety in the synthesis of drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry & Drug Discovery: Used extensively in fragment-based drug design and combinatorial chemistry libraries to explore novel chemical space and improve the pharmacokinetic properties of lead compounds.
• Agrochemical Research: Employed as a building block for developing new generations of herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis in Catalysis: Utilized to construct sophisticated, chelating ligands for asymmetric catalysis and transition metal complexes.
• Advanced Material Science: Acts as a precursor for functionalized polymers and specialty chemicals requiring rigid, amine-functionalized components.

Basic Information

Product Name	2-Aza-Spiro[3.3]Heptan-6-Ol
CAS No.	1256352-97-2
Molecular Formula	C6H11NO
Molecular Weight	113.16 g/mol
Synonyms	6-Hydroxy-2-azaspiro[3.3]heptane; 2-Azaspiro[3.3]heptan-6-ol; 2-Aza-spiro[3.3]heptane-6-ol; Azaspiroheptanol; 6-Hydroxy-2-azabicyclo[3.1.0]hexane (tautomer); 2-Aza-6-ol-spiro[3.3]heptane; 2-N-Azaspiro[3.3]heptan-6-ol
EINECS	Contact for details

Quality Control

Every batch of 2-Aza-Spiro[3.3]Heptan-6-Ol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥95% to ≥98% by HPLC), and impurity profiles. Our quality protocols are designed to support regulatory filings in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C under an inert atmosphere. The compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.