Description

Methyl 2-(Benzyloxycarbonylamino)-2-(Oxetan-3-Yl)Acetate CAS NO 1255717-04-4 is a high-purity, protected amino acid derivative featuring a versatile oxetane ring. This compound serves as a critical advanced pharmaceutical intermediate (API) for the synthesis of complex bioactive molecules. It is primarily required by R&D and production teams in the pharmaceutical and biotechnology sectors for developing novel therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid motifs into peptide chains to enhance metabolic stability and binding affinity.
• Chemical Biology Probes: Serves as a precursor for creating labeled or tagged molecules used in target identification and mechanism-of-action studies.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) exploration by introducing the oxetane moiety, which can improve physicochemical properties like solubility and metabolic stability.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 2-(Benzyloxycarbonylamino)-2-(Oxetan-3-Yl)Acetate
CAS No.	1255717-04-4
Molecular Formula	C14H17NO5
Molecular Weight	279.29 g/mol
Synonyms	Methyl (benzyloxycarbonyl)-3-oxetanylglycinate; Z-3-Oxetaneglycine-OMe; (Z)-3-Oxetaneglycine Methyl Ester; Methyl N-Cbz-3-oxetaneglycinate; 2-[(Benzyloxy)carbonylamino]-2-(oxetan-3-yl)acetic acid methyl ester; Cbz-3-Oxetanegly-OMe; N-Carbobenzoxy-3-oxetaneglycine methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(Benzyloxycarbonylamino)-2-(Oxetan-3-Yl)Acetate adheres to stringent quality protocols suitable for pharmaceutical R&D. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and other critical parameters are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled with care to avoid prolonged exposure. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.