Description

3-Isocyanato-1-Methyl-1,3-Dihydro-2H-Indol-2-One is a specialized isocyanate derivative of the oxindole scaffold, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual functionality, where the reactive isocyanate group enables the formation of ureas and carbamates, while the oxindole core provides a privileged heterocyclic structure. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting neurological disorders and oncology.
• Agrochemical Synthesis: Building block for creating novel herbicides and fungicides with enhanced activity.
• Polymer Chemistry: Used in the production of specialty polyurethanes and polymers with unique thermal or mechanical properties.
• Material Science: Employed in the development of advanced functional materials, including coatings and adhesives.
• Chemical Research: A versatile reagent for academic and industrial R&D in heterocyclic and medicinal chemistry.
• Bioconjugation: Potential use in linking molecules to proteins or other biomolecules via the isocyanate group.

Basic Information

Product Name	3-Isocyanato-1-Methyl-1,3-Dihydro-2H-Indol-2-One
CAS No.	1255147-26-2
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	1-Methyl-3-isocyanatoindolin-2-one; 3-Isocyanato-1-methylindolin-2-one; 1-Methyl-2-oxoindoline-3-isocyanate; N-Methylisatoic anhydride isocyanate; Oxindole-3-isocyanate, 1-methyl-; Isocyanic acid, (1-methyl-2-oxo-2,3-dihydro-1H-indol-3-yl) ester
EINECS	Contact for details

Quality Control

Our 3-Isocyanato-1-Methyl-1,3-Dihydro-2H-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.