Description

Benzyl 6-Hydroxy-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique, constrained bicyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS).
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: Serves as a core structural element in the design and synthesis of potential protease inhibitors.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	Benzyl 6-Hydroxy-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate
CAS No.	1255099-53-6
Molecular Formula	C14H17NO3
Molecular Weight	247.29 g/mol
Synonyms	Benzyl (6-hydroxy-3-azabicyclo[3.1.0]hexan-3-yl)carboxylate; 3-Azabicyclo[3.1.0]hexane-3-carboxylic acid, 6-hydroxy-, benzyl ester; 6-Hydroxy-3-azabicyclo[3.1.0]hexane-3-carboxylic acid benzyl ester; Bicyclo[3.1.0]hexane intermediate; 3-CBz-6-hydroxy-3-azabicyclo[3.1.0]hexane
EINECS	Contact for details

Quality Control

Our Benzyl 6-Hydroxy-3-Azabicyclo[3.1.0]Hexane-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.