Description

3-[5-Iodo-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters for its unique molecular architecture, combining a pyridine core with a substituted pyrazole ring bearing iodine and trifluoromethyl groups, which is critical for modulating biological activity and physicochemical properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry for hit-to-lead optimization and in material science for specialty applications.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the research and development of new drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides, herbicides, and fungicides, leveraging the bioactivity of the pyrazole and pyridine motifs.
• Chemical Biology Probe: Acts as a versatile building block for creating molecular probes to study enzyme function and protein-ligand interactions in biological systems.
• Material Science Research: Employed in the development of advanced organic materials, such as ligands for catalysts or components in organic electronic devices.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-[5-Iodo-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Pyridine
CAS No.	1255041-96-3
Molecular Formula	C9H5F3IN3
Molecular Weight	339.06 g/mol
Synonyms	3-(5-Iodo-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridine; 1-(Pyridin-3-yl)-5-iodo-3-(trifluoromethyl)-1H-pyrazole; 3-(5-Iodo-3-trifluoromethylpyrazol-1-yl)pyridine; Pyridine, 3-[5-iodo-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 1255041-96-3; 3-(5-Iodo-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 3-[5-Iodo-3-(Trifluoromethyl)-1H-Pyrazol-1-Yl]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for pharmaceutical and fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.