Description

2H-Spiro[Furo[2,3-B]Pyridine-3,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and fused heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors working on central nervous system (CNS) targets, kinase inhibitors, and other therapeutic areas. CAS NO 1254981-64-0.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, particularly in preclinical and clinical development stages.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis due to its spirocyclic and piperidine motifs.
• API Development: Used in the process research and scale-up synthesis of potential Active Pharmaceutical Ingredients (APIs) targeting various disease pathways.
• Biochemical Tool Compound: May be utilized in the development of probes and inhibitors for biological target validation in academic and industrial research settings.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client drug discovery programs.

Basic Information

Item	Details
Product Name	2H-Spiro[Furo[2,3-B]Pyridine-3,4'-Piperidine]
CAS No.	1254981-64-0
Molecular Formula	C11H12N2O
Molecular Weight	188.23 g/mol
Synonyms	2H-Spiro[furo[2,3-b]pyridine-3,4'-piperidine]; 2H-Spiro(furo[2,3-b]pyridine-3,4'-piperidine); 2H-Spirofuro[2,3-b]pyridine-3,4'-piperidine; 4'-Piperidine, 2H-spiro[furo[2,3-b]pyridine-3; Spiro[furo[2,3-b]pyridine-3,4'-piperidine]; 1254981-64-0
EINECS	Contact for details

Quality Control

Our 2H-Spiro[Furo[2,3-B]Pyridine-3,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.