Description

1'-Benzyl-2H-Spiro[Furo[2,3-B]Pyridine-3,4'-Piperidine] is a high-value, complex spirocyclic organic compound featuring a fused furopyridine and piperidine scaffold. This sophisticated heterocyclic structure makes it a critical pharmacological building block and key intermediate in modern drug discovery programs. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its privileged spirocyclic architecture.
• CNS Drug Discovery: A key precursor in synthesizing compounds targeting neurological receptors and enzymes.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	1'-Benzyl-2H-Spiro[Furo[2,3-B]Pyridine-3,4'-Piperidine]
CAS No.	1254981-62-8
Molecular Formula	C18H18N2O
Molecular Weight	278.35 g/mol
Synonyms	1'-Benzyl-2H-spiro[furo[2,3-b]pyridine-3,4'-piperidine]; 2H-Spiro[furo[2,3-b]pyridine-3,4'-piperidine], 1'-benzyl-; 1'-Benzylspiro[furo[2,3-b]pyridine-3,4'-piperidine]; Spiro[furo[2,3-b]pyridine-3,4'-piperidine], 1'-benzyl-2H-; 1'-Benzyl-1'H,2H-spiro[furo[2,3-b]pyridine-3,4'-piperidine]; Benzyl-spiro-furopyridine-piperidine; CAS 1254981-62-8
EINECS	Contact for details

Quality Control

Our 1'-Benzyl-2H-Spiro[Furo[2,3-B]Pyridine-3,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full analytical data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.