Description

4-(Benzyloxy)-2-Chloro-3-(Trifluoromethyl)Pyridine is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a halogenated pyridine core with a benzyloxy and a trifluoromethyl group, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in fluorinated compounds.

Basic Information

Product Name	4-(Benzyloxy)-2-Chloro-3-(Trifluoromethyl)Pyridine
CAS No.	1254981-27-5
Molecular Formula	C13H9ClF3NO
Molecular Weight	287.66 g/mol
Synonyms	2-Chloro-3-(trifluoromethyl)-4-(phenylmethoxy)pyridine; 4-(Benzyloxy)-2-chloro-3-trifluoromethylpyridine; 2-Chloro-4-(benzyloxy)-3-(trifluoromethyl)pyridine; Pyridine, 4-(benzyloxy)-2-chloro-3-(trifluoromethyl)-; 1254981-27-5
EINECS	Contact for details

Quality Control

Every batch of 4-(Benzyloxy)-2-Chloro-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.