Description

8-Bromo-6-trifluoromethyl-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is valued for its unique heterocyclic scaffold, which incorporates bromine and trifluoromethyl groups to modulate the pharmacokinetic and binding properties of target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological processes and enzyme functions.
• Agrochemical Development: Potential intermediate for creating new active ingredients in crop protection products.
• Material Science: Exploration of its use in the synthesis of specialty chemicals and functional materials.

Basic Information

Product Name	8-Bromo-6-trifluoromethyl-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester
CAS No.	1254309-85-7
Molecular Formula	C11H7BrF3N2O2
Molecular Weight	335.09 g/mol
Synonyms	Ethyl 8-bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate; 8-Bromo-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic Acid Ethyl Ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 8-bromo-6-(trifluoromethyl)-, ethyl ester; 1254309-85-7; 8-Bromo-6-trifluoromethylimidazo[1,2-a]pyridine-2-ethyl carboxylate
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-trifluoromethyl-imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.