Description

3,3-Dimethyl-1-Oxa-6-Azaspiro[3.3]Heptane 2,2,2-Trifluoroacetate Salt is a high-value, advanced pharmaceutical intermediate and building block with a unique spirocyclic structure. This compound is critical for the synthesis of complex molecules, offering a versatile nitrogen-oxygen heterocyclic core for medicinal chemistry and drug discovery programs. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic scaffold.
• Organic Synthesis: Serves as a versatile precursor for constructing complex nitrogen- and oxygen-containing heterocycles.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Ligand and Catalyst Design: Utilized in the development of novel chiral ligands or organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological targets and pathways.

Basic Information

Product Name	3,3-Dimethyl-1-Oxa-6-Azaspiro[3.3]Heptane 2,2,2-Trifluoroacetate Salt
CAS No.	1254036-08-2
Molecular Formula	C9H12F3NO3
Molecular Weight	239.19 g/mol
Synonyms	3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane trifluoroacetate; 6-Azaspiro[3.3]heptane, 1-oxa-3,3-dimethyl-, 2,2,2-trifluoroacetate (salt); 3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane TFA salt; 1-Oxa-6-azaspiro[3.3]heptane, 3,3-dimethyl-, trifluoroacetate; Spirocyclic amine TFA salt; TFA Salt of 3,3-Dimethyl-1-oxa-6-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our 3,3-Dimethyl-1-Oxa-6-Azaspiro[3.3]Heptane 2,2,2-Trifluoroacetate Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation upon exposure to air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.