Description

1-tert-Butyl 4-Ethyl 4-Formylpiperidine-1,4-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its reactive formyl and ester functional groups. This compound is of significant value for its role as a key building block in the synthesis of complex, bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within the fields of central nervous system (CNS) and metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing piperidine-based compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• CNS Drug Development: Used in the research and production of potential therapeutics targeting neurological receptors and enzymes.
• Chemical Synthesis: Employed in organic synthesis for introducing protected amine and aldehyde functionalities in complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry's outsourced R&D and production needs.

Basic Information

Product Name	1-tert-Butyl 4-Ethyl 4-Formylpiperidine-1,4-Dicarboxylate
CAS No.	1253791-57-9
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	4-Formyl-1,4-piperidinedicarboxylic acid 1-(1,1-dimethylethyl) 4-ethyl ester; tert-Butyl 4-ethyl 4-formylpiperidine-1,4-dicarboxylate; 4-Formylpiperidine-1,4-dicarboxylic Acid 1-tert-Butyl 4-Ethyl Ester; 1-Boc-4-(ethoxycarbonyl)-4-formylpiperidine; 4-Ethoxycarbonyl-4-formylpiperidine-1-carboxylic Acid tert-Butyl Ester; 1-N-Boc-4-ethoxycarbonyl-4-formylpiperidine
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-Ethyl 4-Formylpiperidine-1,4-Dicarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent oxidation and moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.