Description

Ethyl 4-Hydroxy-7-Methyl-2-Oxo-1-(Prop-2-Ynyl)-1,2-Dihydro-1,8-Naphthyridine-3-Carboxylate is a high-purity, synthetic organic compound belonging to the 1,8-naphthyridine class, serving as a critical advanced pharmaceutical intermediate or research chemical. Its complex molecular architecture makes it a valuable building block for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). This product is essential for R&D and manufacturing teams in the pharmaceutical and biotechnology sectors focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology Probes: Serves as a starting material for developing molecular probes to study biological processes and disease mechanisms.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses requiring a functionalized naphthyridine core.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for exploratory chemical and pharmacological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug development projects.

Basic Information

Product Name	Ethyl 4-Hydroxy-7-Methyl-2-Oxo-1-(Prop-2-Ynyl)-1,2-Dihydro-1,8-Naphthyridine-3-Carboxylate
CAS No.	1253791-04-6
Molecular Formula	C15H14N2O4
Molecular Weight	286.28 g/mol
Synonyms	Ethyl 1-(2-Propynyl)-4-hydroxy-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylate; 1,8-Naphthyridine-3-carboxylic acid, 1,2-dihydro-4-hydroxy-7-methyl-2-oxo-1-(2-propynyl)-, ethyl ester; 4-Hydroxy-7-methyl-2-oxo-1-(prop-2-yn-1-yl)-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester; CAS 1253791-04-6; 1-(Prop-2-ynyl)-4-hydroxy-7-methyl-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 4-Hydroxy-7-Methyl-2-Oxo-1-(Prop-2-Ynyl)-1,2-Dihydro-1,8-Naphthyridine-3-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.