Description

4-[1'-(3'-Azido-1',2'-Propanediol)]Carbazole is a specialized carbazole derivative functionalized with an azido-diol moiety, representing a high-value building block for advanced material synthesis. This compound is engineered to serve as a key intermediate in click chemistry and polymer science, where its reactive azide group enables efficient, modular conjugation under mild conditions. It is primarily required by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for developing novel drug conjugates, functional coatings, and smart materials.

Application

• Pharmaceutical Intermediate: Serves as a versatile linker or precursor in the synthesis of targeted drug delivery systems and antibody-drug conjugates (ADCs) via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Polymer & Material Science: A critical monomer for synthesizing functionalized polymers, dendrimers, and hydrogels with tailored properties for coatings, adhesives, and biomedical devices.
• Agrochemical Research: Used in developing novel active ingredients or pro-agrochemicals with enhanced bioavailability or environmental stability.
• Bioconjugation & Probe Development: Facilitates the labeling and modification of biomolecules (proteins, peptides, oligonucleotides) for diagnostic assays and imaging applications.
• Surface Functionalization: Enables the covalent attachment of carbazole-based motifs to nanoparticles, sensors, and chromatographic media to alter surface properties.
• Academic & Industrial R&D: A valuable tool compound for exploring new reactions in synthetic organic chemistry and developing novel materials with photoconductive or electroluminescent properties.

Basic Information

Product Name	4-[1'-(3'-Azido-1',2'-Propanediol)]Carbazole
CAS No.	1253696-17-1
Molecular Formula	C15H14N4O2
Molecular Weight	282.30 g/mol
Synonyms	4-(3-Azido-1,2-dihydroxypropyl)carbazole; 1-(Carbazol-4-yl)-3-azidopropane-1,2-diol; 4-(1,2-Dihydroxy-3-azidopropyl)carbazole; Azido-diol Carbazole Derivative; Carbazole-4-azidopropanediol; Click Chemistry Carbazole Monomer; N/Azido-functionalized Carbazole; 1253696-17-1
EINECS	Contact for details

Quality Control

Our production of 4-[1'-(3'-Azido-1',2'-Propanediol)]Carbazole adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and FT-IR to verify specifications. Quality management is aligned with cGMP principles where applicable, ensuring the material is suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the light-sensitive nature and reactive azide functional group, prolonged exposure to light, heat, or moisture should be avoided. Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.