Description

2-Azabicyclo[2.2.2]Oct-7-Ene-2,6-Dicarboxylic Acid, 2-(Phenylmethyl) Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is critical for enabling complex synthetic routes in medicinal chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of sophisticated drug candidates, including those targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in research and development for constructing molecular scaffolds with specific three-dimensional geometries for structure-activity relationship (SAR) studies.
• Asymmetric Synthesis: Serves as a chiral precursor or auxiliary in the synthesis of enantiomerically pure compounds.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands for catalysis or as a core structure in organocatalysts.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CRMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Azabicyclo[2.2.2]Oct-7-Ene-2,6-Dicarboxylic Acid, 2-(Phenylmethyl) Ester
CAS No.	1253521-31-1
Molecular Formula	C17H17NO4
Molecular Weight	299.32 g/mol
Synonyms	2-(Benzyloxycarbonyl)-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylic Acid; 2-Cbz-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylic Acid; 2-Azabicyclo[2.2.2]oct-7-ene-2,6-dicarboxylic Acid 2-Benzyl Ester; 2-[(Benzyloxy)carbonyl]-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylic Acid; Z-Protected 2-Aza-bicyclo[2.2.2]oct-7-ene-6-carboxylic Acid; 2-Carbobenzyloxy-2-azabicyclo[2.2.2]oct-7-ene-6-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Azabicyclo[2.2.2]Oct-7-Ene-2,6-Dicarboxylic Acid, 2-(Phenylmethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere when not in use to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.