Description

(R)-3-Chloro-2-((4-(Trifluoromethoxy)Benzyl)Oxy)Propyl 4-Methoxybenzoate is a high-purity, chiral organic intermediate of significant interest in advanced chemical synthesis. Its value lies in its unique molecular architecture, featuring a trifluoromethoxy benzyl ether and a 4-methoxybenzoate ester, which makes it a critical building block for constructing complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries who require precise, enantiomerically pure intermediates for drug discovery and crop protection agent development. CAS number 1253202-35-5.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure herbicides, fungicides, and insecticides where specific stereochemistry is crucial for efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique optical or surface properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	(R)-3-Chloro-2-((4-(Trifluoromethoxy)Benzyl)Oxy)Propyl 4-Methoxybenzoate
CAS No.	1253202-35-5
Molecular Formula	C19H18ClF3O5
Molecular Weight	418.79 g/mol
Synonyms	(R)-3-Chloro-2-((4-(trifluoromethoxy)benzyl)oxy)propyl 4-methoxybenzoate; 4-Methoxybenzoic acid (R)-3-chloro-2-[[[4-(trifluoromethoxy)phenyl]methyl]oxy]propyl ester; (R)-1-Chloro-3-((4-(trifluoromethoxy)benzyl)oxy)propan-2-yl 4-methoxybenzoate; (S)-Enantiomer of 3-Chloro-2-((4-(trifluoromethoxy)benzyl)oxy)propyl 4-methoxybenzoate (related); Chiral Trifluoromethoxy Benzyl Ether Ester; CAS 1253202-35-5
EINECS	Contact for details

Quality Control

Our (R)-3-Chloro-2-((4-(Trifluoromethoxy)Benzyl)Oxy)Propyl 4-Methoxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure high enantiomeric excess (ee) and identity confirmation via NMR and mass spectrometry. We provide comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.