Description

Methyl 2-(2,4-Difluorophenyl)Pyridine-4-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its difluorophenyl and pyridine carboxylate structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the difluorophenyl moiety can improve compound stability and efficacy.
• Material Science Precursor: Serves as a starting material for creating specialized ligands and functionalized organic molecules used in catalysis and material synthesis.
• Academic & Contract Research: Essential for medicinal chemistry programs in academic institutions and contract research organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	Methyl 2-(2,4-Difluorophenyl)Pyridine-4-Carboxylate
CAS No.	1251898-50-6
Molecular Formula	C13H9F2NO2
Molecular Weight	249.21 g/mol
Synonyms	Methyl 2-(2,4-difluorophenyl)isonicotinate; 2-(2,4-Difluorophenyl)-4-pyridinecarboxylic acid methyl ester; 4-Pyridinecarboxylic acid, 2-(2,4-difluorophenyl)-, methyl ester; Methyl 2-(2,4-difluorophenyl)-4-pyridinecarboxylate; 1251898-50-6; Methyl 2-(2,4-difluorophenyl)pyridine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-(2,4-Difluorophenyl)Pyridine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom purity requirements for specific research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.