Description

5-Bromo-2-(trimethylsilyl)thieno[2,3-b]pyridine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex organic synthesis. It is primarily utilized in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, liquid crystals, and other advanced electronic materials.
• Chemical Synthesis: The bromo and trimethylsilyl groups offer orthogonal reactivity for sequential cross-coupling reactions (e.g., Suzuki, Stille, Negishi).
• Ligand Development: Useful for constructing complex chelating ligands in catalysis and coordination chemistry.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new reaction pathways.

Basic Information

Product Name	5-Bromo-2-(trimethylsilyl)thieno[2,3-b]pyridine
CAS No.	1251728-93-4
Molecular Formula	C10H12BrNSSi
Molecular Weight	286.27 g/mol
Synonyms	5-Bromo-2-(trimethylsilyl)thieno[2,3-b]pyridine; 2-(Trimethylsilyl)-5-bromothieno[2,3-b]pyridine; Thieno[2,3-b]pyridine, 5-bromo-2-(trimethylsilyl)-; 5-Bromo-2-trimethylsilylthieno[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(trimethylsilyl)thieno[2,3-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.