Description

Methyl2-((1R,5S,6S)-3-Azabicyclo[3.1.0]Hexan-6-Yl)Acetate CAS NO 1251668-97-9 is a high-value, chiral bicyclic building block of significant interest in advanced organic synthesis. This compound is prized for its rigid, three-dimensional scaffold which is instrumental in modulating the pharmacokinetic and pharmacodynamic properties of novel drug candidates. It is primarily utilized by pharmaceutical R&D and fine chemical organizations engaged in the discovery and development of new therapeutic agents, particularly within the central nervous system (CNS) and antiviral domains.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex active pharmaceutical ingredients (APIs) and investigational new drugs.
• Medicinal Chemistry Research: Used to introduce a constrained azabicyclic moiety into molecular libraries for structure-activity relationship (SAR) studies and lead optimization.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes to study enzyme function and receptor interactions due to its unique spatial geometry.
• Advanced Material Synthesis: Potential use as a monomer or building block for specialty polymers with specific structural characteristics.

Basic Information

Product Name	Methyl2-((1R,5S,6S)-3-Azabicyclo[3.1.0]Hexan-6-Yl)Acetate
CAS No.	1251668-97-9
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	Methyl (1R,5S,6S)-3-Azabicyclo[3.1.0]hexane-6-acetate; (1R,5S,6S)-6-(Methoxycarbonylmethyl)-3-azabicyclo[3.1.0]hexane; Methyl 2-[(1R,5S,6S)-3-azabicyclo[3.1.0]hexan-6-yl]acetate; (1R,5S,6S)-3-Azabicyclo[3.1.0]hexane-6-acetic acid methyl ester; 3-Azabicyclo[3.1.0]hexane-6-acetic acid, methyl ester, (1R,5S,6S)-; Bicyclic azetidine derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.