Description

1-Methyl-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid CAS NO 1251165-53-3 is a high-purity heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Material Science: Serves as a precursor for functional organic materials, including ligands for catalysts and components for organic electronics.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and the exploration of new chemical reactions.
• Contract Manufacturing (CMO/CDMO): Supplied to custom synthesis organizations for use in client-directed projects requiring this specific scaffold.

Basic Information

Product Name	1-Methyl-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	1251165-53-3
Molecular Formula	C10H8N2O2
Molecular Weight	188.18 g/mol
Synonyms	1-Methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 1-Methyl-7-azaindole-2-carboxylic acid; 1-Methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 2-Carboxy-1-methyl-7-azaindole; 1-Methyl-7-aza-1H-indole-2-carboxylic acid; 1-Methyl-1H-7-azaindole-2-carboxylic acid; 1-Methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid (CAS 1251165-53-3)
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support development and commercial projects with material that meets stringent in-house specifications aligned with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.