Description

1H-Pyrazolo[3,4-B]Pyridine-6-Carboxylic Acid is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Used as a core scaffold or a functionalized fragment in the design and optimization of kinase-targeted therapeutics.
• Agrochemical Research: Serves as a building block for creating novel active ingredients in crop protection and pest management.
• Material Science: Potential precursor for the synthesis of specialized ligands, dyes, or functional organic materials.
• Academic & Contract Research: Essential for method development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-6-Carboxylic Acid
CAS No.	1251111-24-6
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	6-Carboxy-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-6-carboxylic acid; Pyrazolo[3,4-b]pyridine-6-carboxylic acid; 6-(Carboxy)-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine-6-carboxylate (deprotonated form)
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.