Description

5-Fluoro-n-Isopropylpyridin-2-Amine is a high-purity, fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic incorporation of both fluorine and an isopropylamino group, enabling precise modulation of molecular properties for target-oriented applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents, where the fluorine atom enhances biological activity, metabolic stability, and lipophilicity.
• Ligand & Catalyst Development: Serves as a precursor for nitrogen-containing ligands in transition metal catalysis and organocatalysis.
• Material Science: Employed in the synthesis of functionalized polymers and organic electronic materials that require specific fluorine-substituted aromatic amines.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes due to its derivatizable amine group.
• Custom Synthesis & Scale-Up: Available for contract research organizations (CROs) and chemical development teams requiring reliable, gram-to-kilogram quantities for process optimization and pilot-scale production.

Basic Information

Item	Details
Product Name	5-Fluoro-n-Isopropylpyridin-2-Amine
CAS No.	1251039-74-3
Molecular Formula	C8H11FN2
Molecular Weight	154.19 g/mol
Synonyms	2-Amino-5-fluoro-N-isopropylpyridine; 5-Fluoro-2-(isopropylamino)pyridine; N-Isopropyl-5-fluoropyridin-2-amine; 5-Fluoro-N-(propan-2-yl)pyridin-2-amine; 5-Fluoro-2-isopropylaminopyridine; 2-Pyridinamine, 5-fluoro-N-(1-methylethyl)-; 1251039-74-3
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-n-Isopropylpyridin-2-Amine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets rigorous in-house specifications, supported by a detailed Certificate of Analysis (COA) for each lot. We adhere to cGMP principles where applicable, ensuring traceability and reliability for critical development and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its classification as a fluoride/strong alkali-related compound, ensure the container is kept tightly sealed and stored separately from incompatible materials such as strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.