Description

1-Boc-6-Oxa-1,9-Diazaspiro[3.6]Decane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical companies and research institutions in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry R&D: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Spirocyclic Compound Synthesis: Exploited for constructing complex, three-dimensional molecular architectures that can improve drug-like properties such as solubility and metabolic stability.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring high-fidelity, complex heterocyclic intermediates.

Basic Information

Product Name	1-Boc-6-Oxa-1,9-Diazaspiro[3.6]Decane
CAS No.	1251022-85-1
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	tert-Butyl 6-oxa-1,9-diazaspiro[3.6]decane-1-carboxylate; 1,9-Diazaspiro[3.6]decane-1-carboxylic acid, 6-oxa-, 1,1-dimethylethyl ester; 1-Boc-6-oxa-1,9-diazaspiro[3.6]decane; 1-N-Boc-6-oxa-1,9-diazaspiro[3.6]decane; 1-(tert-Butoxycarbonyl)-6-oxa-1,9-diazaspiro[3.6]decane; 6-Oxa-1,9-diazaspiro[3.6]decane-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-6-Oxa-1,9-Diazaspiro[3.6]Decane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our production adheres to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.