Description

1-Piperidinecarboxylic Acid, 4-(4-Chloro-3H-Imidazo[4,5-C]Pyridin-6-Yl)-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel, small-molecule therapeutics targeting specific biological pathways. It is primarily required by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other targeted oncology treatments. Our supply is backed by stringent quality control to ensure batch-to-batch consistency for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of investigational kinase inhibitors for oncology research.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Employed as a tool compound or ligand in biochemical assays to study enzyme function and inhibition.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic and medicinal chemistry.
• Process Chemistry: Acts as a starting material for developing scalable, GMP-compliant synthetic routes for Active Pharmaceutical Ingredients (APIs).

Basic Information

Item	Details
Product Name	1-Piperidinecarboxylic Acid, 4-(4-Chloro-3H-Imidazo[4,5-C]Pyridin-6-Yl)-, 1,1-Dimethylethyl Ester
CAS No.	1251021-83-6
Molecular Formula	C16H19ClN4O2
Molecular Weight	334.80 g/mol
Synonyms	tert-Butyl 4-(4-chloro-3H-imidazo[4,5-c]pyridin-6-yl)piperidine-1-carboxylate; 6-(1-Boc-piperidin-4-yl)-4-chloro-1H-imidazo[4,5-c]pyridine; BOC-Piperidine-Imidazopyridine Chloride Intermediate; 4-(4-Chloro-1H-imidazo[4,5-c]pyridin-6-yl)piperidine-1-carboxylic acid tert-butyl ester; 1-Boc-4-(4-chloro-3H-imidazo[4,5-c]pyridin-6-yl)piperidine; 1251021-83-6; 4-(4-Chloro-1H-imidazo[4,5-c]pyridin-6-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of 1-Piperidinecarboxylic Acid, 4-(4-Chloro-3H-Imidazo[4,5-C]Pyridin-6-Yl)-, 1,1-Dimethylethyl Ester is produced and tested under a rigorous quality management system. We provide comprehensive analytical data to support its use in regulated environments, including full characterization by NMR, HPLC, and MS. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting purity, identity, and impurity profiles. Our quality standards are designed to meet the demanding requirements of pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.