Description

9-Boc-3-Oxo-2,9-Diaza-Spiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate featuring a protected diazaspirocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) around the spirocyclic core.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of heterobifunctional degraders.
• Chemical Biology Probes: Utilized to create tool compounds for studying enzyme function and biological pathways.
• Agrochemical Research: Intermediate in the development of new active ingredients with novel modes of action.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	9-Boc-3-Oxo-2,9-Diaza-Spiro[5.5]Undecane
CAS No.	1251021-18-7
Molecular Formula	C14H24N2O3
Molecular Weight	268.35 g/mol
Synonyms	tert-Butyl 3-oxo-2,9-diazaspiro[5.5]undecane-9-carboxylate; 2,9-Diazaspiro[5.5]undecan-3-one, 9-(1,1-dimethylethyl) ester; 9-Boc-2,9-diazaspiro[5.5]undecan-3-one; 9-(tert-Butoxycarbonyl)-2,9-diazaspiro[5.5]undecan-3-one; BOC-DASU; BOC-Protected Diazaspiro Undecanone
EINECS	Contact for details

Quality Control

Every batch of 9-Boc-3-Oxo-2,9-Diaza-Spiro[5.5]Undecane is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.