Description

3-Hydroxymethyl-1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine-6-carboxylic acid tert-butyl ester is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially within therapeutic areas targeting the central nervous system and other complex diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with fused pyrazolopyridine scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material or intermediate for scaling up the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds for clients.
• Academic Research: Employed in university and institutional labs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	3-Hydroxymethyl-1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine-6-carboxylic acid tert-butyl ester
CAS No.	1251014-60-4
Molecular Formula	C13H19N3O3
Molecular Weight	265.31 g/mol
Synonyms	tert-Butyl 3-(hydroxymethyl)-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridine-6-carboxylate; 1,4,5,7-Tetrahydro-3-(hydroxymethyl)-6H-pyrazolo[3,4-c]pyridine-6-carboxylic Acid 1,1-Dimethylethyl Ester; 6-(tert-Butoxycarbonyl)-1,4,5,7-tetrahydro-6H-pyrazolo[3,4-c]pyridine-3-methanol; 3-Hydroxymethyl-6-Boc-1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine; Boc-Protected Pyrazolopyridine Methanol Derivative
EINECS	Contact for details

Quality Control

Our 3-Hydroxymethyl-1,4,5,7-tetrahydro-pyrazolo[3,4-c]pyridine-6-carboxylic acid tert-butyl ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development projects with analytical data generated via techniques such as HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.