Description

2-Boc-8-Oxa-2,5-Diaza-Spiro[3.6]Decane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with enhanced biological activity and drug-like properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting complex disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in drug discovery and lead optimization programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or ligand design for novel targeted protein degradation therapeutics.
• CNS Drug Discovery: Employed in the research and development of new treatments for neurological and psychiatric conditions due to its ability to cross the blood-brain barrier.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying enzyme function and cellular signaling pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for clinical trials.

Basic Information

Product Name	2-Boc-8-Oxa-2,5-Diaza-Spiro[3.6]Decane
CAS No.	1251005-80-7
Molecular Formula	C12H21N3O3
Molecular Weight	255.31 g/mol
Synonyms	tert-Butyl 8-oxa-2,5-diazaspiro[3.6]decane-2-carboxylate; 2,5-Diaza-8-oxaspiro[3.6]decane-2-carboxylic acid, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-8-oxa-2,5-diazaspiro[3.6]decane; 2-Boc-8-oxa-2,5-diazaspiro[3.6]decane; Boc-ODD Spirocycle; 8-Oxa-2,5-diazaspiro[3.6]decane-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Boc-8-Oxa-2,5-Diaza-Spiro[3.6]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.