Description

1-Boc-1,6-Diaza-Spiro[3.5]Nonane is a high-purity, protected heterocyclic building block of significant importance in modern synthetic chemistry. Its spirocyclic diaza structure makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies due to its rigid, three-dimensional spirocyclic framework.
• Peptidomimetics & Bioisosteres: Serves as a constrained diamine surrogate to modulate the pharmacokinetic and pharmacodynamic properties of peptide-based drugs.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the development of novel herbicides or pesticides with unique modes of action.
• Ligand Synthesis for Catalysis: Can be utilized to create novel chiral ligands for asymmetric catalysis in fine chemical synthesis.

Basic Information

Product Name	1-Boc-1,6-Diaza-Spiro[3.5]Nonane
CAS No.	1251005-45-4
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	1,6-Diaza-spiro[3.5]nonane-1-carboxylic acid tert-butyl ester; tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate; 1-N-Boc-1,6-diazaspiro[3.5]nonane; 1-(tert-Butoxycarbonyl)-1,6-diazaspiro[3.5]nonane; Boc-1,6-Diaza-Spiro[3.5]Nonane; 1,6-Diazaspiro[3.5]nonane-1-carboxylic acid, 1,1-dimethylethyl ester; 1-Boc-1,6-Diazaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our 1-Boc-1,6-Diaza-Spiro[3.5]Nonane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.