Description

6-Oxo-Octahydro-Pyrrolo[3,4-C]Pyridine-2-Carboxylic Acidtert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex, fused bicyclic structure. This compound is of critical importance for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is primarily required by research institutions and pharmaceutical manufacturers engaged in process development and scale-up for new drug candidates.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial building block for the construction of complex molecules with potential biological activity.
• Research & Development of CNS Drugs: Used in the discovery and development of new therapeutics targeting neurological disorders.
• Antiviral Drug Candidate Development: Employed in the synthesis of novel compounds being evaluated for antiviral properties.
• Process Chemistry & Scale-Up: Utilized by process chemists to develop efficient, scalable synthetic routes for new chemical entities (NCEs).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates.
• Academic and Industrial Research: Used in medicinal chemistry programs to explore structure-activity relationships (SAR).

Basic Information

Product Name	6-Oxo-Octahydro-Pyrrolo[3,4-C]Pyridine-2-Carboxylic Acidtert-Butyl Ester
CAS No.	1251004-07-5
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	tert-Butyl 6-oxo-1,3,3a,4,6,7-hexahydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate; 2H-Pyrrolo[3,4-c]pyridine-2-carboxylic acid, 1,3,3a,4,6,7-hexahydro-6-oxo-, 1,1-dimethylethyl ester; 6-Oxo-hexahydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylic acid tert-butyl ester; (3aR,7aS)-tert-Butyl 6-oxohexahydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate; Bicyclic proline derivative tert-butyl ester; Fused pyrrolidine-pyridinone intermediate
EINECS	Contact for details

Quality Control

Our 6-Oxo-Octahydro-Pyrrolo[3,4-C]Pyridine-2-Carboxylic Acidtert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.