Description

tert-Butyl 9-Oxa-2,6-diazaspiro[4.5]decane-2-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating new therapeutic agents, particularly in areas like central nervous system (CNS) and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, especially those targeting complex biological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Proteolysis Targeting Chimera (PROTAC) Development: The spirocyclic structure can be incorporated into linker designs for bifunctional degrader molecules.
• Chemical Biology Probes: Serves as a core structure for developing selective enzyme inhibitors or receptor modulators for biological target validation.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring a rigid, three-dimensional heterocyclic component.

Basic Information

Product Name	tert-Butyl 9-Oxa-2,6-diazaspiro[4.5]decane-2-carboxylate
CAS No.	1251003-79-8
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	2-[(tert-Butoxy)carbonyl]-9-oxa-2,6-diazaspiro[4.5]decane; 9-Oxa-2,6-diazaspiro[4.5]decane-2-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 2,6-diazaspiro[4.5]decan-2-carboxylate, 9-oxa-; Boc-9-oxa-2,6-diazaspiro[4.5]decane; 2,6-Diazaspiro[4.5]decan-2-carboxylic acid, 9-oxa-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 9-oxa-2,6-diazaspiro[4.5]decane-2-carboxylate; 2-N-Boc-9-oxa-2,6-diazaspiro[4.5]decane
EINECS	Contact for details

Quality Control

Our tert-Butyl 9-Oxa-2,6-diazaspiro[4.5]decane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.