Description

tert-Butyl 8-Oxa-2,5-Diazaspiro[3.5]Nonane-2-Carboxylate is a high-value, heterocyclic building block featuring a spirocyclic scaffold. This compound is crucial for medicinal chemistry research and development, serving as a versatile intermediate for constructing complex molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Scaffold: Used to explore structure-activity relationships (SAR) due to its rigid, three-dimensional spirocyclic structure, which can improve drug-like properties.
• Agrochemical Synthesis: Serves as a building block in the development of advanced crop protection agents and pesticides.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic & Institutional Research: Employed in university and research institute laboratories for fundamental organic synthesis and methodology development.

Basic Information

Product Name	tert-Butyl 8-Oxa-2,5-Diazaspiro[3.5]Nonane-2-Carboxylate
CAS No.	1251002-01-3
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	2-[(1,1-Dimethylethoxy)carbonyl]-2,8-diazaspiro[4.5]decan-3-one; 8-Oxa-2,5-diazaspiro[3.5]nonane-2-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 2,8-diazaspiro[4.5]decane-3-one-2-carboxylate; 2,8-Diazaspiro[4.5]decan-3-one, 2-(tert-butoxycarbonyl)-; 2-Boc-2,8-diazaspiro[4.5]decan-3-one; 2-(tert-Butoxycarbonyl)-2,8-diazaspiro[4.5]decan-3-one; 2,8-Diazaspiro[4.5]decan-3-one, N-Boc-protected; Spirocyclic Boc-protected diaza compound
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Oxa-2,5-Diazaspiro[3.5]Nonane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for advanced research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.