Description

1,6-Diaza-Spiro[3.5]Nonane-6-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures that are difficult to achieve with simpler scaffolds. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders and other therapeutic applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially for CNS-targeted therapies.
• Medicinal Chemistry: Used as a versatile scaffold for constructing complex, three-dimensional molecular libraries in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional molecules for targeted protein degradation.
• Chemical Biology Research: Employed in the synthesis of probes and tool compounds for studying biological pathways and enzyme functions.
• Agrochemical Synthesis: Can be utilized in the development of new active ingredients with enhanced biological activity for crop protection.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge synthetic organic chemistry research.

Basic Information

Product Name	1,6-Diaza-Spiro[3.5]Nonane-6-Carboxylic Acid tert-Butyl Ester
CAS No.	1251002-00-2
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	1,6-Diazaspiro[3.5]nonane-6-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 1,6-diazaspiro[3.5]nonane-6-carboxylate; 1,6-Diaza-spiro[3.5]nonane-6-carboxylic acid tert-butyl ester; 6-Boc-1,6-diazaspiro[3.5]nonane; Boc-1,6-diazaspiro[3.5]nonane; 1,6-Diazaspiro[3.5]nonane, 6-Boc-protected; 1,1-Dimethylethyl 1,6-diazaspiro[3.5]nonane-6-carboxylate
EINECS	Contact for details

Quality Control

Our 1,6-Diaza-Spiro[3.5]Nonane-6-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support our clients' regulatory needs and can supply material suitable for use in GMP (Good Manufacturing Practice) environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.