Description

2-Hydroxymethyl-1,4,6,7-Tetrahydro-Imidazo[4,5-C]Pyridine-5-Carboxylic Acid tert-Butyl Ester is a sophisticated heterocyclic building block and key synthetic intermediate in advanced organic chemistry. This compound is valued for its unique fused imidazo-pyridine core, which is integral to constructing complex molecular architectures with specific biological activity. It is primarily sought after by research institutions and pharmaceutical development teams engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Organic Synthesis Building Block: Serves as a protected, functionalized intermediate for constructing complex nitrogen-containing heterocycles.
• Agrochemical Development: Potential use in the research and synthesis of novel crop protection agents and herbicides.
• Bioconjugation & Probe Synthesis: The hydroxymethyl group offers a handle for further chemical modification, useful in creating biochemical probes or labeled compounds.

Basic Information

Product Name	2-Hydroxymethyl-1,4,6,7-Tetrahydro-Imidazo[4,5-C]Pyridine-5-Carboxylic Acid tert-Butyl Ester
CAS No.	1251000-69-7
Molecular Formula	C13H19N3O3
Molecular Weight	265.31 g/mol
Synonyms	tert-Butyl 2-(hydroxymethyl)-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine-5-carboxylate; 1,4,6,7-Tetrahydro-2-(hydroxymethyl)imidazo[4,5-c]pyridine-5-carboxylic Acid 1,1-Dimethylethyl Ester; 5H-Imidazo[4,5-c]pyridine-5-carboxylic acid, 1,4,6,7-tetrahydro-2-(hydroxymethyl)-, 1,1-dimethylethyl ester; 2-Hydroxymethyl-1,4,6,7-tetrahydro-imidazo[4,5-c]pyridine-5-carboxylic acid t-butyl ester
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through modern analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and development documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.