Description

3-Aminomethyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology industries working on central nervous system (CNS) agents, kinase inhibitors, and other therapeutic small molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly in oncology and neurology.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile pyrazolopyridine scaffold.
• API Synthesis: Integral in multi-step synthetic routes for the production of complex target molecules in preclinical and clinical development.
• Chemical Biology Research: Employed as a probe or tool compound in biochemical assays to study specific biological pathways and target interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	3-Aminomethyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester
CAS No.	1251000-58-4
Molecular Formula	C13H22N4O2
Molecular Weight	266.34 g/mol
Synonyms	tert-Butyl 3-(aminomethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate; 5H-Pyrazolo[4,3-c]pyridine-5-carboxylic acid, 3-(aminomethyl)-1,4,6,7-tetrahydro-, 1,1-dimethylethyl ester; 3-(Aminomethyl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester; BOC-protected 3-aminomethyl-pyrazolopyridine; Pyrazolopyridine intermediate 1251000-58-4
EINECS	Contact for details

Quality Control

Our production of 3-Aminomethyl-1,4,6,7-tetrahydro-pyrazolo[4,3-c]pyridine-5-carboxylic acid tert-butyl ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.