Description

3-Aminomethyl-1,7-Dioxa-10-Aza-Spiro[4.6]Undecane-10-Carboxylic Acid tert-Butyl Ester is a sophisticated spirocyclic building block featuring a protected amino acid moiety. This compound is valued for its structural complexity and versatility as a key intermediate in advanced organic synthesis. It is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) or requiring spirocyclic scaffolds.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the spirocyclic structure can confer unique biological activity and stability.
• Chemical Biology & Proteomics: Serves as a specialized scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Advanced Material Science: Potential precursor for creating novel polymers or ligands with specific chelating or catalytic properties.
• Academic & Contract Research: Essential for synthetic methodology development and the exploration of new chemical space in academic and industrial R&D laboratories.

Basic Information

Product Name	3-Aminomethyl-1,7-Dioxa-10-Aza-Spiro[4.6]Undecane-10-Carboxylic Acid tert-Butyl Ester
CAS No.	1251000-10-8
Molecular Formula	C14H25NO5
Molecular Weight	287.35 g/mol
Synonyms	tert-Butyl 3-(aminomethyl)-1,7-dioxa-10-azaspiro[4.6]undecane-10-carboxylate; 10-Boc-3-aminomethyl-1,7-dioxa-10-azaspiro[4.6]undecane; 3-(Aminomethyl)-1,7-dioxa-10-azaspiro[4.6]undecane-10-carboxylic acid 1,1-dimethylethyl ester; Boc-protected spirocyclic amino ester; Spirocyclic Boc-amino acid derivative
EINECS	Contact for details

Quality Control

Our production of 3-Aminomethyl-1,7-Dioxa-10-Aza-Spiro[4.6]Undecane-10-Carboxylic Acid tert-Butyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.