Description

3,4-Dihydro-1H-[2,7]Naphthyridine-2,5-Dicarboxylicacid2-tert-Butylester is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1250999-71-3. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for therapeutic areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of final Active Pharmaceutical Ingredients (APIs) requiring the naphthyridine core structure.
• Chemical Biology Probes: Employed in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	3,4-Dihydro-1H-[2,7]Naphthyridine-2,5-Dicarboxylicacid2-tert-Butylester
CAS No.	1250999-71-3
Molecular Formula	C15H18N2O4
Molecular Weight	290.32 g/mol
Synonyms	2-(tert-Butyl) 5H-3,4-dihydro-1H-[2,7]naphthyridine-2,5-dicarboxylate; 2-tert-Butyl 3,4-dihydro-1H-[2,7]naphthyridine-2,5-dicarboxylate; 1H-[2,7]Naphthyridine-2,5-dicarboxylic acid, 3,4-dihydro-, 2-(1,1-dimethylethyl) ester; 1250999-71-3; tert-Butyl 3,4-dihydro-1H-[2,7]naphthyridine-2-carboxylate-5-carboxylic acid (mixed anhydride form); [2,7]Naphthyridine derivative
EINECS	Contact for details

Quality Control

Our 3,4-Dihydro-1H-[2,7]Naphthyridine-2,5-Dicarboxylicacid2-tert-Butylester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are available for each lot to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.