Description

5-Oxo-7-Phenyl-2,6-Diaza-Spiro[3.4]Octane-2-Carboxylic Acid tert-Butyl Ester is a sophisticated spirocyclic building block of significant interest in modern pharmaceutical and agrochemical research. Its unique molecular architecture, featuring a spiro center and a protected carboxylic acid, makes it a versatile intermediate for constructing complex, three-dimensional scaffolds. This compound is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. Its reliable synthesis and consistent quality are critical for accelerating drug discovery pipelines and ensuring reproducible results in advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the spirocyclic structure can contribute to novel modes of action and improved environmental profiles.
• Chemical Biology Probe Synthesis: Employed to create specialized molecular tools for studying enzyme function and protein-protein interactions within biological systems.
• Methodology Development: Acts as a challenging substrate for developing new catalytic asymmetric synthesis and spirocyclization methodologies in academic and industrial settings.
• Peptidomimetic Chemistry: The diaza-spiro structure is valuable for designing conformationally constrained peptide analogs with enhanced stability and bioavailability.

Basic Information

Product Name	5-Oxo-7-Phenyl-2,6-Diaza-Spiro[3.4]Octane-2-Carboxylic Acid tert-Butyl Ester
CAS No.	1250999-70-2
Molecular Formula	C17H22N2O3
Molecular Weight	302.37 g/mol
Synonyms	tert-Butyl 5-oxo-7-phenyl-2,6-diazaspiro[3.4]octane-2-carboxylate; 2,6-Diaza-spiro[3.4]octane-2-carboxylic acid, 5-oxo-7-phenyl-, 1,1-dimethylethyl ester; 5-Oxo-7-phenyl-2,6-diazaspiro[3.4]octane-2-carboxylic acid tert-butyl ester; 7-Phenyl-5-oxo-2,6-diazaspiro[3.4]octane-2-carboxylic acid tert-butyl ester; Spirocyclic diaza building block CAS 1250999-70-2
EINECS	Contact for details

Quality Control

Every batch of 5-Oxo-7-Phenyl-2,6-Diaza-Spiro[3.4]Octane-2-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of process chemistry and research applications. A comprehensive Certificate of Analysis (COA) detailing all critical quality attributes is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.