Description

2-[(tert-Butoxy)Carbonyl]-2-Azaspiro[3.3]Heptane-5-Carboxylic Acid is a high-value, multifunctional building block in advanced organic synthesis, prized for its rigid spirocyclic and protected amine architecture. This compound is critical for medicinal chemistry research, enabling the rapid construction of complex molecular scaffolds with enhanced three-dimensional properties. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex, three-dimensional molecular frameworks.
• Peptidomimetic Chemistry: Used to incorporate constrained, non-natural amino acid analogs into peptide chains to enhance metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds and probes to study enzyme function and protein-protein interactions.
• Agrochemical Research: Employed in the discovery and development of new generation pesticides and herbicides that require specific stereochemistry and functional group presentation.
• Ligand Synthesis for Catalysis: Utilized in the preparation of sophisticated chiral ligands for asymmetric catalysis, leveraging its spirocyclic core to induce stereoselectivity.
• Material Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal and mechanical properties.

Basic Information

Product Name	2-[(tert-Butoxy)Carbonyl]-2-Azaspiro[3.3]Heptane-5-Carboxylic Acid
CAS No.	1250999-54-2
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	5-Carboxy-2-[(tert-butoxy)carbonyl]-2-azaspiro[3.3]heptane; 2-Azaspiro[3.3]heptane-5-carboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]-; 2-(tert-Butoxycarbonyl)-2-azaspiro[3.3]heptane-5-carboxylic acid; 2-Boc-2-azaspiro[3.3]heptane-5-carboxylic acid; Boc-Azaspiro[3.3]heptane-5-COOH; 2-(Boc)-2-azaspiro[3.3]heptane-5-carboxylic acid; tert-Butyl 5-carboxy-2-azaspiro[3.3]heptane-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of 2-[(tert-Butoxy)Carbonyl]-2-Azaspiro[3.3]Heptane-5-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.