Description

9-Boc-5-Oxa-2,9-Diazaspiro[3.6]Decane is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies and contract research organizations (CROs) engaged in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring a constrained spirocyclic amine moiety.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing focused libraries to explore structure-activity relationships (SAR) in early-stage drug discovery.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker component due to its rigid, three-dimensional structure and functional handles for conjugation.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for target identification and validation studies.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic and spirocyclic chemistry.

Basic Information

Product Name	9-Boc-5-Oxa-2,9-Diazaspiro[3.6]Decane
CAS No.	1250998-79-8
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	tert-Butyl 5-oxa-2,9-diazaspiro[3.6]decane-9-carboxylate; 2,9-Diazaspiro[3.6]decane, 9-[(1,1-dimethylethoxy)carbonyl]-5-oxa-; 9-Boc-5-oxa-2,9-diazaspiro[3.6]decane; Boc-ODD Spirocycle; 5-Oxa-2,9-diazaspiro[3.6]decane-9-carboxylic acid tert-butyl ester; Spirocyclic Boc-protected amine ether
EINECS	Contact for details

Quality Control

Our 9-Boc-5-Oxa-2,9-Diazaspiro[3.6]Decane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.