Description

2-Cbz-9-Boc-2,9-Diazaspiro-[5.5]Undecane-3-Carboxylicacid CAS NO 1250992-79-0 is a high-purity, advanced pharmaceutical intermediate featuring a complex diazaspirocyclic scaffold. This compound is of critical importance for medicinal chemists in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for constructing sophisticated molecular architectures.

Application

• Key Intermediate in Drug Discovery: Serves as a crucial building block for synthesizing potential drug candidates targeting G protein-coupled receptors (GPCRs) and other biological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize the pharmacological profile of new chemical entities.
• Synthesis of Bioactive Molecules: The protected carboxylic acid and amine functionalities make it versatile for peptide-mimetic and constrained scaffold synthesis.
• Library Synthesis for High-Throughput Screening: Employed in the generation of focused compound libraries for screening against various disease targets.
• Process Chemistry Development: Used during the scale-up and route optimization phases for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Cbz-9-Boc-2,9-Diazaspiro-[5.5]Undecane-3-Carboxylicacid
CAS No.	1250992-79-0
Molecular Formula	C23H32N2O6
Molecular Weight	432.51 g/mol
Synonyms	2-[(Benzyloxy)carbonyl]-9-[(tert-butoxy)carbonyl]-2,9-diazaspiro[5.5]undecane-3-carboxylic acid; 2-Cbz-9-Boc-2,9-diazaspiro[5.5]undecane-3-carboxylic acid; 2,9-Diazaspiro[5.5]undecane-3-carboxylic acid, 2-[(phenylmethoxy)carbonyl]-9-[(1,1-dimethylethoxy)carbonyl]-; UNII-9V4V8N2B4F; 9V4V8N2B4F; 2-Cbz-9-Boc-2,9-diazaspiro[5.5]undecane-3-carboxylate; 2,9-Diazaspiro[5.5]undecane-3-carboxylic acid derivative; Spirocyclic Diamine Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our 2-Cbz-9-Boc-2,9-Diazaspiro-[5.5]Undecane-3-Carboxylicacid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.