Description

5-Nitro-1,2-Dihydrospiro[Indole-3,4'-Oxane] is a specialized spirocyclic indole derivative, a high-value synthetic intermediate of significant interest in advanced organic synthesis. Its unique fused-ring structure containing both nitro and indole moieties makes it a critical building block for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials due to its electron-deficient nitroaromatic group.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.

Basic Information

Product Name	5-Nitro-1,2-Dihydrospiro[Indole-3,4'-Oxane]
CAS No.	1250991-93-5
Molecular Formula	C12H12N2O3
Molecular Weight	232.24 g/mol
Synonyms	5-Nitrospiro[indoline-3,4'-oxane]; 5-Nitro-1,2-dihydrospiro[indole-3,4'-oxane]; 1,2-Dihydro-5-nitrospiro[indole-3,4'-oxane]; Spiro[indoline-3,4'-oxan]-5-amine, N-oxide?; 5-Nitrospiro[indole-3,4'-tetrahydropyran]; 1250991-93-5; 5-Nitro-1,2-dihydro-spiro[indole-3,4'-oxane]
EINECS	Contact for details

Quality Control

Our 5-Nitro-1,2-Dihydrospiro[Indole-3,4'-Oxane] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.